深圳市仙湖植物园;仙湖

学习、进修经历：

2002 　生物信息博士，北京大学
1997 生物学士，北京大学

研究领域：

所涉及的领域与科学问题，包括“什么是基因？”，“各种进化压力下基因如何进化？”，“基因与复杂性表型的关联?”以及基因组包括组装、注释、比较、多态性、表达、表观遗传、调控和进化在内的各种数据分析、工具和数据库开发。

获奖及荣誉：

2009 广东省“五一”劳动奖章
2008 广东省“五一”劳动奖章
2008 中国十大科技进展新闻奖：炎黄一号基因组图谱
2008 国务院及深圳市政府特殊津贴人员
2008 赛默飞世尔特约之2008年度生命科学十大风云人物
2007 His Royal Highness Prince Foundation (Denmark): Award for Science and Sino-Danish Collaboration
2006 新世纪百千万人才工程国家级人选
2006 The Danish Research Council: Young Elite Scientist
2005 The Lundbeck Foundation: Talent Price
2004　　　中国科学院研究生院优秀教师和优秀课程
2003　　　中国科学院杰出科技成就奖
2003 　 “中央国家机关优秀青年”称号
2003　　　中国十大科技进展新闻奖－SARS科技攻关项目
2002 　香港求是科技基金求是杰出科技成就集体奖
2003 北京大学东盛科学论文奖
2002 　北京大学学术十杰
复旦大学谈家桢基金生命科学九源奖学金一等奖
2002 中国科学院重大创新贡献奖
2002 教育部全国优秀博士论文
2002　　　中国十大科技进展新闻奖－水稻基因组精细图和水稻第四号染色体精确测序图
2001　　　中国十大科技进展新闻奖 －水稻基因组工作框架图
2001　　　中国十大科技进展新闻奖 －人类基因组计划“中国卷”

承担（参与）科研项目情况：

1999年，王俊教授在人类基因组计划中承担了中国部分的数据分析工作。随后于2001年，在中国籼稻基因组计划中负责生物信息学分析部分。包括水稻基因组组装、注释、表达、复制、比较基因组学、分子进化、转录调控、多态性等多个方面。王俊教授同时还致力于脊椎动物中的基因注释问题和非编码基因问题。在2003-2004年还参与了SARS 基因组分析，组织实施了家蚕、家猪基因组计划与家鸡多态性图谱计划。2007年组织实施完成了第一个黄种人的基因组图谱计划（炎黄计划）。发展了RePS、ReAS、SOAP等数十个引用率很高的序列分析软件算法，开发了十几个数据库。
王俊教授现正组织实施个体人类基因组计划、千人基因组计划、糖尿病基因组计划、胃肠道元基因组计划、熊猫基因组计划以及多个多态性图谱计划（包括水稻、蚕和猪基因组）等。

发表论著：

*第一作者 ‡通讯作者
1、 M. Rasmussen, … J. Wang‡, E. Willerslev. 2010. The Diploid Genome of an Extinct Palaeo-Eskimo. Nature (in press)
2、 J. Qin, … J. Wang‡. 2010. A human gut microbial gene catalog established by deep metagenomic sequencing. Nature (in press)
3、 R. Li, … J. Wang‡. 2009. De novo assembly of the human genomes with massively parallel short read sequencing. Genome Research Dec 17. [Epub ahead of print]
4、 R. Li, … J. Wang‡. 2009. The sequence and de novo assembly of the giant panda genome. Nature Dec 13. [Epub ahead of print]
5、 R. Li, … J. Wang‡, J. Wang. 2009. Building the sequence map of the human pan-genome. Nature Biotechnology Dec 07. [Epub ahead of print]
6、 S. Huang, … J. Wang‡, Y. Du, S. Li. 2009. The genome of the cucumber (Cucumis sativus Linnaeus). Nature Genetics 41:1275-81.
7、 Q. Xia, … J. Wang‡. 2009. Complete Resequencing of 40 Genomes Reveals Domestication Events and Genes in Silkworm (Bombyx). Science 326: 433-6.
8、 J. Duan, … J. Wang, et al. 2009. SilkDB v2.0: a platform for silkworm (Bombyx mori ) genome biology. Nucleic Acids Res. Sep 30. [Epub ahead of print]
9、 Y. Li, J. Wang‡. 2009. Faster human genome sequencing. Nature Biotechnology. 27:820-1.
10、 R. Li, … J. Wang‡. 2009. SOAP2: an improved ultrafast tool for short read alignment. Bioinformatics 25:1966-7.
11、 X. Chen, … J. Wang, et al. 2009. Identification and characterization of novel amphioxus microRNAs by Solexa sequencing. Genome Biol. 10: R78.
12、 Y. Zhou, … J. Wang, et al. 2009. The Schistosoma japonicum genome reveals features of host–parasite interplay. Nature 460: 345-51.
13、 R. Li, … J. Wang‡. 2009. SNP detection for massively parallel whole genome resequencing. Genome Research 19:1124-32.
14、 J. Li, … J. Wang‡. 2009. Correlation between Ka/Ks and Ks is related to substitution model and evolutionary lineage. J Mol Evol. 68:414-23.
15、 M. Schierup, … J. Wang, et al. 2009. Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups. BMC Med Genet. 3:10-20
16、 L. Ma, … J. Wang‡, et al. 2009. The YH database: the first Asian diploid genome database. Nucleic Acids Res. 37:D1025-8.
17、 J. Wang, as one of the authors in the International Silkworm Genome Consortium. 2008. The genome of a lepidopteran model insect, the silkworm Bombyx mori. Insect Biochem Mol Biol. 38:1036-45.
18、 J. Wang‡, et al. 2008. The diploid genome sequence of an Asian individual. Nature 456: 60-5.
19、 W. Muir, … J. Wang, et al. 2008. Genome-wide assessment of worldwide chicken SNP genetic diversity indicates significant absence of rare alleles in commercial breeds. Proc. Natl. Acad. Sci. USA [Epub ahead of print].
20、 X. Chen, … J. Wang‡, et al. 2008. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 18:997-1006.
21、 Q. Zhou, J. Wang*, et al. 2008. Neo-sex chromosomes in the black muntjac recapitulate incipient evolution of mammalian sex chromosomes. Genome Biology 9:R98.
22、 R. Li, … J. Wang‡. 2008. SOAP: short oligonucleotide alignment program. Bioinformatics 24:713-4.
23、 X. Zou, ... J. Wang, et al. 2008. Analysis of 142 genes resolves the rapid diversification of the rice genus. Genome Biology 9:R49.
24、 S. Xu, … J. Wang‡, X. Zheng. 2008. Gene conversion in the rice genome. BMC Genomics 9:93.
25、 L. Fang, ... J. Wang‡. 2008. Positive correlation between recombination rate and nucleotide diversity is shown under domestication selection in the chicken genome. Chin. Sci. Bull. 53: 746-50.
26、 J. Ruan, … J. Wang‡, R. Durbin. 2008. TreeFam: 2008 Update. Nucleic Acids Res. 36:D735-40. a) Clark, ... J. Wang, et al. 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450:203-18.
27、 H. Li, ... J. Wang‡. 2007. A cross-species alignment tool (CAT). BMC Bioinformatics 8:349.
28、 X. Wang, J. Wang, et al. 2007. The complete mitochondrial genome of the Chinese hook snout carp Opsariichthys bidens (Actinopterygii: Cypriniformes) and an alternative pattern of mitogenomic evolution in vertebrate. Gene. 399:11-9.
29、 H. Zheng, … J. Wang‡. 2007. FGF: a web tool for Fishing Gene Family in a whole genome database. Nucleic Acids Res. 35:W121-5.
30、 X. He, J. Wang‡. 2007. BGI-RIS V2: Rice Information System at the Beijing Genomics Institute. Methods Mol Biol. 406:275-300.
31、 G. Zhang, G., … J. Wang, et al. 2007. Identification and characterization of insect-specific proteins by genome data analysis. BMC Genomics 8:93.
32、 J. Gorodkin, ... J. Wang, et al. 2007. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 ESTs. Genome Biology 8:R45.
33、 C. Chen, ... J. Wang, et al. 2007. A Glimpse of Streptococcal Toxic Shock Syndrome from Comparative Genomics of S. suis 2 Chinese Isolates. PLoS ONE. 2:e315.
34、 S. Li, ... J. Wang‡. 2007. Snap: an integrated SNP annotation platform. Nucleic Acids Res. 35:D707-10
35、 J. Ruan, ... J. Wang‡. 2007. PigGIS: Pig Genomic Informatics System. Nucleic Acids Res. 35:D654-7
36、 Y. Zhang, ... J. Wang, M. Mann. 2007. MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes. Nucleic Acids Res. 35:D771-9
37、 X. Qi, ... J. Wang‡, B. Su. 2007. Detecting positive darwinian selection in brain-expressed genes during human evolution. Chinese Science Bulletin. 52:324-335
38、 X. Yu, … J. Wang, et al. 2006. Detecting lineage-specific adaptive evolution of brain-expressed genes in human using rhesus macaque as outgroup. Genomics. 88:745-751
39、 W. Wang, … J. Wang‡. 2006. High Rate of Chimeric Gene Origination by Retroposition in Plant Genomes. Plant Cell. 18:1791-802.
40、 Z. Zhang, … J. Wang, et al. 2006. KaKs_Calculator: calculating Ka and Ks through model selection and model averaging. Genomics Proteomics Bioinformatics. 4:259-63.
41、 X. Wang, … J. Wang, R. Yang. 2006. Genomic comparison of Yersinia pestis and Yersinia pseudotuberculosis by combination of suppression subtractive hybridization and DNA microarray. Arch Microbiol. 186:151-9.
42、 J. Ye, … J. Wang‡. 2006. WEGO: a web tool for plotting GO annotations. Nucleic Acids Res. 34:W293-7.
43、 Z. Peng, J. Wang, S. He. 2006. The complete mitochondrial genome of the helmet catfish Cranoglanis bouderius (Siluriformes: Cranoglanididae) and the phylogeny of otophysan fishes. Gene. 376:290-7.
44、 D. Muzny, … J. Wang, et al. 2006. The DNA sequence, annotation and analysis of human chromosome 3. Nature. 440:1194-8.
45、 H. Li, … J. Wang‡, R. Durbin. 2006. TreeFam: a curated database of phylogenetic trees of animal gene families. Nucleic Acids Res. 34:D572-80.
46、 L. Li, … J. Wang, X. Deng. 2006. Genome wide transcription analyses in rice using tiling microarrays. Nature Genetics. 38:124-129.
47、 Z. Peng, … J. Wang, … R. Diogo. 2006. Mitochondrial molecular clocks and the origin of the major Otocephalan clades (Pisces: Teleostei): A new insight. Gene 370:113-24
48、 R. Li, … J. Wang‡. 2005. Recovery of ancestral sequences for transposable elements from the unassembled reads of a whole genome shotgun. PLoS Comput Biol 1: e43.
49、 W. Wang, … J. Wang‡. 2005. Origin and revolution of new exons in rodents. Genome Res. 15: 1258-1264.
50、 L. Ma, … J. Wang, et al. 2005. A microarray analysis of the rice transcriptome and its comparison to Arabidopsis. Genome Res. 15: 1274-1283.
51、 V. Stolc, … J. Wang, X. Deng. 2005. A pilot study of transcription unit analysis in rice using oligonucleotide tiling-path microarray. Plant Molecular Biology 59:137-149.
52、 L. Li, … J. Wang, et al. 2005. Tiling microarray analysis of rice chromosome 10 to identify the transcriptome and relate its expression to chromosomal architecture. Genome Biology 6:R52.
53、 S. Lee, ... J. Wang, et al. 2005. Detecting novel low-abundant transcripts in Drosophila. RNA. 11: 939-46.
54、 R. Wernersson, … J. Wang, et al. 2005. Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genomics 6:70.
55、 Y. Wang, … J. Wang, et al. 2005. Accelerated evolution of the pituitary adenylate cyclase-activating polypeptide precursor gene during human origin. Genetics 170: 801-806.
56、 Z. Tong, … J. Wang, et al. 2005. Pseudogene accumulation might promote the adaptive microevolution of Yersinia pestis. J Med Microbiol. 54: 259-268.
57、 J. Yu, J. Wang*, et al. 2005. The genomes of Oryza sativa: A history of duplications. [Cover Story]. PLoS Biology 3: e38.
58、 S. Xu,... J. Wang, et al. 2005. A mitochondrial genome sequence of the Tibetan antelope (Pantholops hodgsonii). Genomics Proteomics Bioinformatics 3: 5-17.
59、 J. Wang, … J. Wang‡. 2005. ChickVD: a sequence variation database in the chicken genome. Nucleic Acids Res. 33: D438-D441.
60、 J. Wang, … J. Wang, et al. 2005. SilkDB: a knowledgebase for silkworm biology and genomics. Nucleic Acids Res. 33: D399-D402.
61、 L. Kang, … J. Wang, et al. 2004. The analysis of large-scale gene expression correlated to the phase changes of the migratory locust. Proc. Natl. Acad. Sci. USA 101: 17611-17615.
62、 Q. Xia, … J. Wang*, et al. 2004. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science 306: 1937-1940.
63、 G.K. Wong, B. Liu, J. Wang*, et al. 2004. A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature 432: 717-722.
64、 J. Wang, as one of the authors in the International Chicken Genome Sequencing Consortium. 2004. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432: 695-716.
65、 J. Wang, as one of the authors in the International Human Genome Sequencing Consortium. 2004. Finishing the euchromatic sequence of the human genome. Nature 431: 946-957.
66、 J. Wang, et al. 2004. Neutral evolution of “non-coding” cDNAs from the mouse transcriptome. Nature 431: 1 p following 757.
67、 Z. Li, ... J. Wang, et al. 2004. Detailed comparison between the wheat chromosome group 7 short arms and the rice chromosome arms 6S and 8L with special reference to genes involved in starch biosynthesis. Funct Integr Genomics. 4: 231-40.
68、 Y. Song, … J. Wang, et al. 2004. Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans. DNA Research 11, 179-197.
69、 C. Li, … J. Wang, et al. 2004. Genes controlling seed dormancy and pre-harvest sprouting in a rice-wheat-barley comparison, Funct Integr Genomics. 4: 84-93.
70、 J. Tang, … J. Wang, et al. 2004. A comparison of rice chloroplast genomes. Plant Physiol. 135: 412-20. a) Tian, J. Wang*, et al. 2004. Characterization of soybean genomic features by analysis of its expressed sequence tags. Theor Appl Genet. 108: 903-13.
71、 W. Zhao, … J. Wang‡. 2004. BGI-RIS: an integrated information resource and comparative analysis workbench for rice genomics. Nucleic Acids Res. 32: D377-D382.
72、 J. Wang, et al. 2003. Vertebrate gene predictions and the problem of large genes. Nature Rev. Genet. 4: 741-749.
73、 J. Xu, ... J. Wang, et al. 2003. Genome organization of the SARS-CoV. Genomics Proteomics Bioinformatics 1: 226-35.
74、 J. Hu, ... J. Wang, et al. 2003. Evolution and variation of the SARS-CoV genome. Genomics Proteomics Bioinformatics 1: 216-25.
75、 S. Bi, ... J. Wang, et al. 2003. Complete genome sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04). Genomics Proteomics Bioinformatics 1: 180-92.
76、 Z. Xu, ... J. Wang, et al. 2003. The R protein of SARS-CoV: analyses of structure and function based on four complete genome sequences of isolates BJ01-BJ04. Genomics Proteomics Bioinformatics 1: 155-65.
77、 Q. Wu, ... J. Wang, et al. 2003. The E protein is a multifunctional membrane protein of SARS-CoV. Genomics Proteomics Bioinformatics 1: 131-44.
78、 E. Qin, ... J. Wang, et al. 2003. A genome sequence of novel SARS-CoV isolates: the genotype, GD-Ins29, leads to a hypothesis of viral transmission in South China.Genomics Proteomics Bioinformatics 1: 101-7.
79、 E. Qin,… J. Wang, et al. 2003. A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01). Chin. Sci. Bull. 48: 941-948.
80、 L. Zhong,... J. Wang, et al. 2003. A statistical approach designed for finding mathematically defined repeats in shotgun data and determining the Length distribution of clone-inserts. Genomics Proteomics Bioinformatics 1: 43-57.
81、 Y. Zhou, ... J. Wang, et al. 2003. Gene identification and expression analysis of 86,136 Expressed Sequence Tags (EST) from the rice genome. Genomics Proteomics Bioinformatics 1: 26-42.
82、 G.K. Wong, J. Wang, et al. 2002. Compositional gradients in Gramineae genes. [Cover Story]. Genome Res. 12: 851-856.
83、 J. Wang‡, et al. 2002. RePS: a sequence assembler that masks exact repeats identified from the shotgun data. Genome Res. 12: 824-831.
84、 X. Zhang, … J. Wang, et al. 2002. Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene. Gene 288: 9-18.
85、 J. Yu, S. Hu, J. Wang*, et al. 2002. A draft sequence of the rice genome (Oryza sativa L. ssp. indica) [Cover Story]. Science 296: 79-92.
86、 J. Yu, S. Hu, J. Wang*, et al. 2001. A draft sequence of the rice (Oryza sativa ssp. indica) genome. Chin. Sci. Bull. 46: 1937-1942.
87、 J. Wang, as one of the authors in the International Human Genome Sequencing Consortium. 2001. Initial sequencing and analysis of the human genome. Nature 409: 860-921.
88、 J. Wang, S. Li. 2001. Artificial intelligent work for imitating the evolution of lady beetle’s searching behavior, Chinese Journal of Ecology 20: 65-69.