Name: Feng Shixiu 
Highest Education: PH.D.
Post: Senior Engineer; Assistant Research Fellow
Phone: +86 755 25734040
Email: [email protected]

EDUCATION    
2011.8 – now      Research associate, Key Laboratory of Southern Subtropical Plant Diversity Shenzhen Fairy Lake Botanical Garden, Chinese Academy of Sciences.
2008.09 − 2011.07  Ph.D., Program for Natural Product Medicinal Chemistry, South China Botanical Garden, Chinese Academy of Sciences, China
2010.09 − 2011.03  Visiting Scholar, Jack Bell Research Center, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada
2005.09 − 2008.07  M.Sc., Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, China
2001.09 − 2005.07 Bachelor of Agronomy, Department of Agronomy, Northwest Sci-Tech University of Agriculture & Forestry, China   

RESEARCH INTERESTS
My research focuses on natural product medicinal chemistry, mainly on Chinese Traditional Herbal Medicines. China has diverse plant resources and long history of using them as therapeutic agents. Some of these herbal medicines have potential efficacy on cancer disease, some have significant anti-inflammatory activity, some are helpful for promoting immune system. My research interest focuses on secondary metabolites from Chinese traditional medicines:
a) Isolate the chemical constituents and evaluate their bioactivities
b) Elucidate the structure-activity relationship.
c) Find out the leading compounds and interpret their functional mechanisms.
d) Structure modification of the leading compounds.
During my studies, over 200 bioactive compounds including flavonoids, triterpenoids, xanthones, anthraquinones and steroids have been investigated. Some of them showed potent anti-cancer activity and their in vitro and in vivo mechanisms are being studied.
MAIN PUBLICATIONS

• Shixiu Feng, Lidong Lin, Hanhong Xu and Xiaoyi Wei. Two new peperidine alkaloids from the leaves of Microcos paniculata. Journal of Asian Natural Products Research. 2008, 10(12): 1155-1158.
• Shixiu Feng, Lidong Lin, Meifang Liu, AND Xiaoyi Wei. Triterpenoids and flavonoids from the leaves of Microcos paniculata. Journal of Tropical and Subtropical Botany. 2008, 16(1): 51-56.
• Hongxin Wu, Xiaoyi Wei, Shixiu Feng, Alamus, Tianming Hu, Yuqing Wang. A study on the flavonoids of Lespedeza hedysaroides. Acta Botanica Boreali-occidentalia Sinica. 2009, 9: 1904-1908.
• Shixiu Feng, Liangxiong Xu, Min Wu, Jing Hao, Samuel X. Qiu, Xiaoyi Wei. A New coumarin from Sarcandra glabra. Fitoterapia. 2010, 81, 472-474.
• Jing Hao, Shixiu Feng, Shengxiang Qiu, Tao Chen. Anthraquinone Glycosides from the Roots of Prismatomeris connata. Chinese Journal of Natural Medicines. 2011. 9(1): 42-45.
• Shixiu Feng, Jing Hao, Tao Chen, and Samuel X. (Shengxiang) Qiu. A New Anthraquinone and Two New Tetrahydroanthraquinones from the Roots of Prismatomeris connata.Helvetica Chimica Acta. 2011, 94: 1843-1849.
• Jing Hao, Ying Pei, Guiyuan Ji, Weijie Li, Shixiu Feng, Shengxiang Qiu. Autophagy is induced by 3β-O-succinyl-lupeol (LD9-4) in A549 cells via up-regulation of Beclin 1 and down-regulation mTOR pathway. European Journal of Pharmacology. 2011, 670(1): 29-38.
• Shixiu Feng, Jing Hao, Zhifang Xu, Tao Chen and Samuel X. (Shengxiang) Qiu. Polyprenylated Isoflavanone and Isoflavonoids from Ormosia henryi and Their Cytotoxic and Anti-oxidation Activity. Fitoterapia. 2012, 83: 161-165.
• Shixiu Feng, Jijiang Bai, Shengxiang Qiu (Samuel), Yong Li, Tao Chen. Iridoid and phenolic glycosides from the roots of Prismatomeris connata. Natural Compounds Communication. 2012, 7: 1-2.
• Shixiu Feng, Qiunong Guan, Tao Chen, Caigan Du. In vitro activities of 3-hydroxy-1,5,6-trimethoxy-2-methyl-9,10-anthraquinone against non-small cell lung carcinoma. Archives of Pharmacal Research. 2012, 35: 1251-1258.
• Manqin Fu, Shixiu Feng, Riming Huang, Nenling Zhang, Xiaojun Zhou, Samuel X. Qiu. A new prenylated isoflavone and a new flavonol glycoside from Flemingia philippinensis. Helvetica Chimica Acta. 2012, 95(4).
• Cunli Zhang, Shixiu Feng, Lanxi Zhang, Zhanjun Ren. A new cytotoxic steroidal saponin from the rhizomes and roots of Smilax scobinicaulis. Natural Product Research. 2013, 27(14): 1255-1260.
• Shixiu Feng, Feng Liu, Jiong Li, Shengxiang Qiu, Tao Chen. A new bixanthone derivative from the bark of Garcinia oblongifolia. Natural Product Research. 2014, 28(2): 81-85.